There is an interesting discussion at Google Webmaster Help forums where a new site at microbialgenomics.org, which is the Center for Infectious Disease Genomics run by Washington University in St. Louis is marked with a manual action for "pure spam."
The issue seems to have been that the original domain name was used by a spammer and it had a manual action for pure spam.
But Susanna Siebert, the person responsible at the Center for Infectious Disease Genomics said she submitted a reconsideration request and it was rejected.
After days of back and forth with SEOs in the thread, Google's very own Eric Kuan came in to tell Susanna that this is an error on Google's end. He wrote:
It looks like there may have been an error when processing your reconsideration request. We're re-processing it now, and you should see a change in the Manual Actions Viewer in the next couple of days.
I am sure this is a big relief for Susanna and her team but all that wasted time and efforts over a processing error on Google's end...
Forum discussion at Google Webmaster Help.